have been several theories presented over the past few decades to
help explain why drinking Noni juice may produce a wide range of
positive health responses in the human body:
- One proposed explanation is related to a recently
discovered alkaloid called “xeronine”,
that is proposed to work at the cellular level to modify and strengthen
the structure of proteins in our cells.
- Another theory is that Noni contains a unique selection
of polysaccharide compounds that are able to stimulate
and enhance the body’s own natural immune system.
- Noni has also been shown to encourage the body
to produce nitric oxide that may aid in fighting tumors
and viral, bacterial and parasitic infections.
The common theme running
through these theories is that Noni acts as a catalyst in the human body
for production of the body’s own natural functions to achieve and
maintain optimal health. This natural health boost makes drinking Noni
juice an excellent compliment to any diet.
The "Xeronine System"
a New Biochemical System
The “Xeronine System” was the term created
for the first scientific explanation of Noni fruit's effectiveness in
aiding the healing of a diverse number of ailments and diseases in the
human body. A scientist by the name of Dr. Ralph Heinicke originally
began to formulate the idea of a new bio-system he named the Xeronine
System while working in Hawaii at the Pineapple Research Institute during
The Discovery of Xeronine in Hawaiian Pineapples
During this time, Dr. Heinicke was hired to find
a new method to isolate bromelain enzymes from pineapples to be sold
to companies in a variety of industries that included the food and pharmaceutical
industries. Dating back to the 18th Century, bromelain is one of the
earliest known enzymes used for tenderizing meat.
Before Dr. Heinicke, many people had attempted to
isolate bromelain but failed. It was not until the early 1950’s
when he solved the problem in his research of the pineapple and was able
to get a patent assigned to the Pineapple Research Institute, that the
bromelain enzyme could be produced commercially.
Reports from customers started to come in of unexpected
and beneficial medicinal effects that bromelain extracts were producing
in their bodies. It was determined that an unknown active ingredient
must be present in bromelain and causing the desirable actions in those
who had been taking it.
Through continued research, Dr. Heinicke discovered
a substance that he called “proxeronine”. He did not know
how it worked, only that it clearly contributed to bromelain extract’s
Heinicke eventually found that proxeronine, combined
with another enzyme he called “proxeroninase”, formed an
active ingredient in the body that was not a protein, carbohydrate or
fat, but a substance known as an alkaloid, a nitrogenous organic molecule
that has a pharmacological effect on humans and other mammals.
Dr. Heinicke was able to isolate the alkaloid into
a pure state and found it to be a dry crystalline structure, so he used
the Latin prefix “xero” meaning “dry” as the
first part of the new name, and due to its alkaline nature, he added
the suffix “ine” to make the word “Xeronine,” which
means dry alkaline compound.
Heinicke proposed that when released in
the body, Xeronine works at the molecular level to repair damaged cells
by regulating the rigidity and shape of proteins at the cellular level
of the body.
The Dole Pineapple Company began to market and produce
commercial bromelain extracts and wanted to be the market leader, so
Dr. Heinicke was asked by the company’s president to watch for
other natural products that a competitor could use to produce the same
pharmacological actions in people. At the time, 1956, the only other
plant known to rival bromelain potency was Noni fruit, but because it
was not commercially grown, Dr. Heinicke did not see it as a competitor.
In further research, Dr. Heinicke found Noni fruit
to be the most abundant source of proxeronine available in a plant, containing
40 times more proxeronine than pineapples. He also found Noni to contain
one other enzyme, proxeronase, that combines with proxeronine in the
liver to create Xeronine.
The Effects of Xeronine in the Human Body
The proteins in your body’s cells are made
up of organic material. Some of these hold you together like your skin,
hair, and bones. Others at the cellular level, are the functional proteins
that help cells do work such as enzymes, hormones, antibodies and cell
Xeronine is believed to have profound effects on
the functional proteins in your body that may explain the broad influence
Noni has on the different systems in your body.
How does all this
aid sick cells? It was not until
Dr. Heinicke came together with a medical doctor, Dr. Neil Solomon, that
the application of this knowledge was made to the healing of disease.
Dr. Heinicke and Dr. Solomon, who received his clinical training in medicine
at Johns Hopkins Hospital in Baltimore, Maryland combined forces to develop
the “Heinicke-Solomon Theory”.
The theory explains from a
medical perspective how Noni juice is converted in the body to produce
Xeronine that is theorized to help sick cells resume normal function.
The Heinicke-Solomon Theory Explains the Beneficial
Effects of Noni
According to their Heinicke-Solomon Theory, when
Noni juice is consumed, it first travels through the digestive tract
into the liver. Whenever any food is digested, the liver sorts out what
the body will absorb and what will be eliminated, such as toxins. In
the case of Noni juice, the proxeronine gathers in the liver and is packaged
with other bio-chemicals, then released to the rest of the body through
In theory, at the cellular level of your body, the Golgi Apparatus
(GA) plays the central role in aiding a sick or malfunctioning cell.
In cell biology, the GA is found in most cells including plants, animals
and fungi. The primary function of the GA is to process proteins and
functions as a central delivery system for the cell.
Once in the GA, the proxeronine and other bio-chemicals
are combined and sent out to the sick cell. The “package” of
biochemicals is unpacked and the proxeronine is combined with the enzyme,
proxerionase, that is then converted to Xeronine. The creation of the
Xeronine alkaloid is what is believed to create the adaptogenic
compound used to help a specific cell to regain a state of homeostasis that leads
the body back to a balanced state of health.
The theory suggests Noni’s natural ability
to create an adaptive resistance at the cellular level in the human body
may help abnormally functioning or damaged cells to reach a balanced
state and resume normal function while allowing healthy functioning cells
to resist adverse influences from biochemical factors to maintain normal
NONI – The Human Body's
Natural Immune System Booster
Noni juice is an important and powerful food supplement
to add to your diet because of its ability to stimulate your immune system
into action. By drinking it daily, your body’s immune system is
optimized to respond against the invasion of outside germs, bacteria
and viruses as it fights them off and protects you from infection.
Scientific research studies conducted at the Burns
School of Medicine at the University of Hawaii discovered that Noni juice
contains a polysaccharide-rich substance that has been shown to boost
the body’s immune system by increasing the activity of white blood
Furthermore, Noni also has been found to stimulate the body’s
ability to create Nitric Oxide (NO) inside your body to kill bacteria,
viral and parasitic infections. The compounds found in Noni fruit simply
act as a catalyst to stimulate the body’s own natural immune-system
Your immune system is what protects your body from
the outside environment by maintaining a barrier of entry before the
bacteria, germ or virus enters your body. Sometimes these invaders get
past the first line of defense and that is when your immune system goes
to work to detect and eliminate the invaders before they are able to
reproduce and cause serious problems for you, the host. The white blood
cells are the primary component of your immune system and it is their
job to destroy these foreign invaders.
This is done by the white blood
cells producing protective antibodies that will overpower the foreign
invaders by surrounding and devouring them before they can cause any
damage to the body.
Activate the Immune System
The polysaccharide element of Noni juice is called “noni-ppt” and
has been shown in scientific research studies to increase the release
of immune-enhancing compounds that activate white blood cells. In a study
conducted at the University of Hawaii on mice, the polysaccharides, or
noni-ppt, prolonged the life of inbred tumor-bearing mice, which led
the researcher to conclude the polysaccharide substance from Noni suppressed
tumor growth by activating the host’s immune system.
Noni Stimulates the Body’s
Nitric Oxide Production, Protecting the Body from Infection
In laboratory trials conducted at the University
of Hawaii, Noni was shown to stimulate the body to produce Nitric Oxide
(NO) and have a profound effect on the immune system. Over the past two
decades, nitric oxide has come to be recognized as a major influence
of the immune system’s ability to protect the body from infection.
In the past, nitric oxide was regarded as an environmental pollutant
that was a byproduct of the exhaust fumes of cars and other combustion
Recently, researchers have found that nitric oxide
produced in the body helps to activate macrophages, the cells in the
body that are activated when an injury or illness occurs. They seek out
and destroy invading parasites, bacteria and other potentially infectious
invaders that pose a threat to the body.
How Noni worked probably
never entered into the minds of the ancient ancestors of today’s
Hawaiians, who first brought the Noni plants from Tahiti as their medicinal
fruit of choice, 1,600 years ago.
The Hawaiian “Kahuna” (medicine
man) from long ago was a highly specialized expert in pharmacology and
used the Noni fruit to treat the people of his time for a wide range
of ailments. He probably never understood how the chemistry in the fruit
aided the healing process of those in his care, but these early physicians
could understand the importance of Noni fruit to the healthful benefits
of their patients.
What the ancient
Hawaiians knew and used, as an antidote for numerous ailments for centuries
to aid the body’s natural healing functions is now available today
fresh sealed in a pharmaceutical grade HDPE bottle conveniently delivered to your front door.
of TRU NONI is simple: use only fresh ripe Noni fruit grown in the Hawaiian
Islands with all the healthful active compounds that can only be called TRU